Yongde (David) Zhang
lab responsibilities (areas of expertise):
vascular smooth muscle biology:
arterial K+ currents
(1) Characterizing the basal ion currents in human radial artery, as well as the electrophysiological response to clinically relevant pharmacological tools
(alpha-adrenergic agonists, nitric oxide donors, anti-hypertensives).
(2) Exploring isoprostanes (metabolites of membrane lipid peroxidation) as possible candidates for endothelium-derived hyperpolarizing factor and/or endothelium-derived contracting factor